Biopharm Services

News from BPS


Feb 2012: New Technology Grant

1 FEB 2012: Biopharm Services has been awarded a UK Technology Strategy Board grant to develop our software bioprocess database application to support rapid bioprocess development and technology transfer to manufacturing. Extending the functionality of the BioSolve platform to recipe management and facility fit.


New Newsletter published

New Newsletter published October 2011. Gives details of the exciting changes happening with the BioSolve Suite.


Annual Bioprocess Simulation prize

Biopharm Service's Annual Bioprocess Simulation prize was awarded in November 2011 to a team of undergraduate students at UCL's Department of Biochemical Engineering for their work on "Application of BioSolve computer simulation tool for investigating the process economics of antibody production". The BioSolve modelling tool was used to evaluate the economics of a process to produce an IgG antibody for treating arthritis and to understand impact of scale-up to and for process optimisation. This demonstrates the value of BioSolve to help students within the teaching programmes at UCL to understand the impact of process and technology choices.
Download the UCL BioSolve poster


Past President of the IChemE joins the Biopharm Team

Bioprocess specialist Stephen Vranch joins Biopharm Services. Since 1968 Stephen has held senior positions in Project and Process Engineering, Fermentation and Process Development and in Production of Diagnostics and Biological Therapeutic Pharmaceuticals, including licensed bulk product. Stephen was a former President of the IChemE. As our lead consultant, Stephen specialises on all aspects of CGMP regulatory compliance.


BioSolve

BioSolve used to generate data for GE lifecycle assessment of the entire monocloncal antibody production process: a comparison of multi-use and single-use processes. Upcoming webinar

Adoption of BioSolve Process in UCL Biochemical Engineering Courses

BioPharm Services is pleased to announce the adoption of BioSolve Process by the Biochemical Engineering Department of University College London (UCL). The cost modelling software has been used for both undergraduate and postgraduate courses including the MBI® programme (Modular Training for the Bioprocess Industries). MORE »



CLIENT RELATIONSHIPS

Publications for Engineering Design

Click a title to download the document in PDF or Word format.

Building a facility around disposables, choice and challenges

Author: Olivier Cochet, Head of Industrial Biotechnology department, Pierre Fabre

User Viewpoints on Disposables Implementation

Authors: Andrew Sinclair, Miriam Monge
Biopharm International; June 2009

Disposables Cost Contributions: A Sensitivity Analysis

Authors: Andrew Sinclair, Miriam Monge
Biopharm International; April 2009

Evaluating Disposable Mixing Systems

Authors: Andrew Sinclair, Miriam Monge
Biopharm International; February 2009

Disposable Technologies Implementation: Understanding and Managing Risks

Authors: Andrew Sinclair, Miriam Monge
Biopharm International; December 2008

The Environmental Impact of Disposable Technologies

Authors: Andrew Sinclair, Lindsay Leveen, Miriam Monge, Janice Lim, Stacey Cox
Biopharm International; November 2008

Disposables Open Up Possibilities in Facility Design

Authors: Andrew Sinclair, Miriam Monge
Biopharm International; August 2008

How to Evaluate the Cost Impact of Using Disposables in Biomanufacturing

Author: Andrew Sinclair
Biopharm International; June 2008

Disposable Bioreactors: The Next Generation

Authors: Andrew Sinclair
Biopharm International; April 2008

Concept Facility Based on Single-Use Systems, Part 2: Leading the Way for Biomanufacturing in the 21st Century

Authors: Andrew Sinclair, Miriam Monge
Biopharm International; October 2005

A Framework for Assessing the Solutions in Chromatographic Process Design and Operation for Large Scale Manufacture

Authors: A Framework for Assessing the Solutions in Chromatographic Process Design and Operation for Large Scale Manufacture
Journal of Chemical Technology and Biotechnology; Editorial ref. code: JCTB-05-0411.R1, Article Identifier at Wiley (AID): JCTB1508

Biomanufacturing for the 21st Century: Designing a Concept Facility Based on Single-Use Systems, Part 1

Authors: Andrew Sinclair, Miriam Monge
Biopharm International; October 2004

Bioreactor System Design Edited by Juan A. Asenjo, José C. Merchuk; Chapter 15 Sterilisation and Containment

Authors: Andrew Sinclair, Mike Ashley
CRC Press, 1995 ISBN 0824790022, 9780824790028

The Specification of Static Seals for Contained Operations: An Engineering Appraisal

Authors: Titchener-Hooker N.J, Sinclair P.A., Hoare M, Vranch S.P., Cottam A, Turner M.K.
Pharmaceutical Technology Europe 1993

Rapid Implementation of a Smallpox Vaccine Facility

Authors: Karin Wassard, Miriam Monge
Bioprocess International: May 2007

Successful Project management for Implementing Single-Use Bioprocessing systems

Authors: Miriam Monge
Biopharm International; November 2006

Disposable Technologies for Aseptic Filling

Authors: Jan-Eric Zandbergen, Miriam Monge
Bioprocess International June 2006

Single-use bag manifolds: applications

Authors: Miriam Monge
World Pharmaceutical Developments: 2002

Disposable technology for biopharmaceutical manufacturing

Authors: Miriam Monge, Hans Preusting, Hans Kuyvenhoven
World Pharmaceutical Developments, 2001 Vol2

Design and optimization of manufacturing. In: Gottschalk U, editor. Process scale purification of antibodies

Authors: Andrew Sinclair
Hoboken: John Wiley and Sons, Inc. pp. 263 - 291

Using disposables in an antibody production process: a cost-effectiveness study of technology transfer between two production sites

Authors: Auriele Foulon, Frank Trach, Alan Pralong, Mark Proctor, Janice Lim
Bioprocess International, June 2008