Biopharm Services

News from BPS


Feb 2012: New Technology Grant

1 FEB 2011: Biopharm Services has been awarded a UK Technology Strategy Board grant to develop our software bioprocess database application to support rapid bioprocess development and technology transfer to manufacturing. Extending the functionality of the BioSolve platform to recipe management and facility fit.


New Newsletter published

New Newsletter published October 2011. Gives details of the exciting changes happening with the BioSolve Suite.


Annual Bioprocess Simulation prize

Biopharm Service's Annual Bioprocess Simulation prize was awarded in November 2011 to a team of undergraduate students at UCL's Department of Biochemical Engineering for their work on "Application of BioSolve computer simulation tool for investigating the process economics of antibody production". The BioSolve modelling tool was used to evaluate the economics of a process to produce an IgG antibody for treating arthritis and to understand impact of scale-up to and for process optimisation. This demonstrates the value of BioSolve to help students within the teaching programmes at UCL to understand the impact of process and technology choices.
Download the UCL BioSolve poster


Past President of the IChemE joins the Biopharm Team

Bioprocess specialist Stephen Vranch joins Biopharm Services. Since 1968 Stephen has held senior positions in Project and Process Engineering, Fermentation and Process Development and in Production of Diagnostics and Biological Therapeutic Pharmaceuticals, including licensed bulk product. Stephen was a former President of the IChemE. As our lead consultant, Stephen specialises on all aspects of CGMP regulatory compliance.


BioSolve

BioSolve used to generate data for GE lifecycle assessment of the entire monocloncal antibody production process: a comparison of multi-use and single-use processes. Upcoming webinar

Adoption of BioSolve Process in UCL Biochemical Engineering Courses

BioPharm Services is pleased to announce the adoption of BioSolve Process by the Biochemical Engineering Department of University College London (UCL). The cost modelling software has been used for both undergraduate and postgraduate courses including the MBI® programme (Modular Training for the Bioprocess Industries). MORE »



Meet the Team


Andrew Sinclair

Andrew Sinclair
President & Founder

Andrew has over 20 years design experience in the biopharmaceutical industry, from the first recombinant insulin process through to large scale monoclonal antibody manufacturing. He has had direct experience of and responsibility for manufacturing, logistics, maintenance and capital programme management.

Most recently he was Director of Engineering and Logistics at Lonza Biologics. Andrew has an MSc in Biochemical Engineering from University College London. He has published widely and has presented at numerous industry conferences.


Claire O'Beirne

Claire O'Beirne
Company Secretary

Claire manages the company accounts and payroll and ensures compliance with relevant legislation and regulation. As Company Secretary, Claire also advises on HR policies and procedures.


Miriam Monge

Miriam Monge
Vice President, Global Key Accounts

Miriam has over 20 years international experience in the biopharmaceutical manufacturing sector. Miriam joined Biopharm Services following 14 years with Sartorius Stedim Biotech where in her role as Marketing Director she worked closely with Biopharm Services to develop a design and implementation approach for disposables into biomanufacturing. Miriam founded the ISPE disposables community of practice of which she has just completed a 3 year tenure as Chair, she is a regular presenter at International conferences and has published widely notably co-authoring two regular industry columns, the 'disposables advisor' in Biopharm International and a manufacturing economics column 'delivering affordable biologics from gene to vial' in Bioprocess International.

Miriam holds an MBA from the Ecole Superieure de Commerce in Marseille and is a Senior Visiting lecturer at MBI continuous education biomanufacturing training courses, University College London.


Yuki Abe

Yuki Abe
Modelling Specialist

Yuki focuses on modelling innovative bioprocesses, engineering design and evaluate the economic impact of design and applications. She graduated with a PhD in Biochemical Engineering and a MEng in Biochemical Engineering with Bioprocess Management at UCL, London. Her PhD research focused on the use of biophysical methods to analyse the stability and the structure of a MAb under a range of bioprocess conditions.

Highlight of her research was mainly based on the use of small angle x-ray solution scattering and analytical ultracentrifugation as additional to more conventional analytical techniques. Also she acquired basic knowledge of UNIX. She got IBM Business Consulting award (2005) and a Derek Robert Scholarship (2003) during her undergraduate degree from the department.


David Wareheim

David Wareheim
Process Specialist

Dave Wareheim is a process specialist with over 25 years design and operational experience in the biopharmaceutical industry. Dave has had responsibility for the development and tech transfer of a number of biopharm products. Of particular relevance is his experience in the use of process mapping for analyzing parametrics, organizing the upstream and downstream steps, and his extensive process modelling experience ranging from DCS configuration to enterprise workflow mapping.

Prior to joining Biopharm Dave was an Engineering Research Fellow Johnson & Johnson Pharmaceutical R&D. David has a BSc in Biology, he has published widely and has presented at numerous industry conferences, and has provided innovative solutions to process needs.


Stephen Vranch

Stephen Vranch
Manager Regulatory Compliance

Responsible for advising on Regulatory Compliance of facilities and processes for the manufacture of pharmaceuticals, including biopharmaceuticals and vaccines. Advice includes biosafety requirements for pathogens and genetically modified organisms.


Andrew Brown

Andrew Brown
Head of Software Applications and Senior Consultant Engineer

Head of software applications for the development and application of the BioSolve Software Suite. Andrew has extensive experience of bioprocess modeling and the economic implications of innovative process design and application of new technologies. Consultancy areas also include manufacturing strategy, market analysis for new technologies, engineering design including single-use process design and biopharmaceutical facility layout. He is a biochemical engineering graduate with an EngD in Biochemical Engineering and Bioprocess Management from UCL, London. His research focused on the process development, modeling and scale-up of membrane filtration systems.


Andrea Rayat

Andrea Rayat
BioSolve Product Manager and Consultant Engineer

Andrea focuses primarily on the development and product management of BioSolve, working directly to support the BioSolve User base. She is a chemical engineer with a background in biotechnological and chemical processes. She has experience in the scale-up of membrane processes, design of membrane devices, process analysis involving antibody fragments production, bioparticles, and other bioproducts. She has been involved in engineering design, process and economic modelling, technology assessment, biotechnology business planning as well as in engineering education. She was a research engineer and teaching assistant at University College London and, before that, was a lecturer in chemical engineering in the Philippines. Andrea has a PhD in Biochemical Engineering from UCL, and an MSc in (Bio)Chemical Engineering from Delft University of Technology.


Claire Burden

Claire Burden
Consultant Engineer

Claire focuses on engineering design, modelling bioprocesses and the economic implications of innovative design and applications. She is a biochemical engineering graduate with an EngD in Biochemical Engineering and Bioprocess Management at UCL. Her research focused on primary purification and chromatography. She has GMP production experience within manufacturing environments for vaccines and therapeutics.


Siraj Zarook

Siraj Zarook
Lead Software Developer

Siraj is the lead developer for BioSolve Process and the research programme to develop future applications to support process development and tech transfer within the biologics industry. He has a strong track record in leading, managing and delivering software development projects. In his career Siraj worked for one of the UK’s leading software solution providers and delivered solutions to process credit card applications for major UK banks for 7 years from 2004. He was also the key for maintaining and enhancing of company’s online invoice processing system. As a part of streamlining the existing process he played a major role in migrating legacy systems onto the latest Microsoft .Net platforms which also helped to enhance the security aspects of the system. During this development he worked with internal personnel who were maintaining the ISO 27001 standards for the organization.