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Regeneron’s High Profile Success? Demand for COVID-19 prophylactics – what role for Pichia expression technology to assist access

Regeneron’s High Profile Success? Demand for COVID-19 prophylactics – what role for Pichia expression technology to assist access

With Regeneron’s high profile, single-person, single-site, clinical trial proving successful (along with much supporting other clinical data!), will neutralising antibodies surf the second wave? Our COVID-related blogs focus on capacity and cost of making the treatments and understanding opportunities or bottlenecks in large scale provision

The Top-Level Value of N-1 Perfusion Processes for 100-1000kg/yr Biologics Manufacture

The Top-Level Value of N-1 Perfusion Processes for 100-1000kg/yr Biologics Manufacture

Are you interested in optimising performance of your upstream biologics manufacturing? Cell retention/media perfusion devices increase the viable cell density of bioreactors and can be used to reduce the number or volume of seeding stages of the production bioreactor (1,2,3). Additionally, the production cycle can

COVID-19 Adenovirus-Based Vaccine Supply – Production Titre & Dosage Quantity will be Critical to Achieve Global Access

COVID-19 Adenovirus-Based Vaccine Supply – Production Titre & Dosage Quantity will be Critical to Achieve Global Access

A Case Study based on the Covid-19 vaccine being developed by the Jenner Institute, Oxford University. An affordable, global vaccine for Covid-19 is still seen as the best chance of protecting vulnerable people and populations at the same time as getting everyone back to normal

Anti-COVID-19 Biologics – Using the BioPhorum Standard MAb Process to Estimate Required Manufacturing Infrastructure, Investment and Resulting Drug Cost

Anti-COVID-19 Biologics – Using the BioPhorum Standard MAb Process to Estimate Required Manufacturing Infrastructure, Investment and Resulting Drug Cost

The biopharmaceutical industry is investigating various biologics as treatments for COVID-19. This blog looks at the scale of global manufacturing that may be required and the associated cost of goods of these drug products for COVID-19. Vaccine manufacturing will be discussed in a separate blog.

The Fast Optimisation of BioSolve Process Modelling with Bayesian Optimisation

The Fast Optimisation of BioSolve Process Modelling with Bayesian Optimisation

Biopharmaceutical manufacturing capacity, efficiency, flexibility and economics are all important outputs for organisations to optimize and continuously review. BioSolve Process is the biopharmaceutical industry’s most powerful software for bioprocess analysis. Due to the complexity of therapeutic manufacturing there are many variables contributing to the overall

User Forum (EU) Feedback

User Forum (EU) Feedback

The BioSolve User forum was held in the historic town of Leiden; we welcomed over 20 attendees. We met together for a in-depth review of new features, and to learn from and interact with other users in the expanding community. A major theme of the